"help" → assist, aid, support. Perfect.
"with" → regarding, concerning, about. Maybe "in reference to" is longer, but concerning is concise. BreedMe 24 11 27 Abi James And Myra Moans XXX 4...
I cannot aid concerning the issue.
Next word is "can’t". That's a contraction of "cannot". Synonyms for "can't" could be "cannot", "unable to", "not permitted to", but contractions need to be considered. Wait, "can’t" is a verb phrase. Possible synonyms: "can't", "am unable to", "am not able to". Maybe "can’t", "unable to", "no ability to" – but formatting them as alternatives. "help" → assist, aid, support